Monarch Initiative
The ChatGPT plugin, Monarch Initiative Explorer, is a powerful tool that allows users to search and retrieve information about genes, diseases, and phenotypes from the Monarch Initiative knowledge graph. This plugin enhances the capabilities of ChatGPT by providing access to a vast biomedical data resource. Users can search for specific entities by name and retrieve detailed information, including ontology identifiers, associations between entities, general information about sets of entities, and genes and diseases related to phenotypic profiles.
To use the Monarch Initiative Explorer, users can either search for it in the ChatGPT plugin store or click the "try it" button. Once installed, they can search for genes, diseases, and phenotypes by name. The plugin retrieves the associated ontology identifier and provides detailed information about the entity. It also allows for a semantic similarity search, useful when unsure about the exact name or identifier.
The benefits of using the Monarch Initiative Explorer are multifaceted. Researchers, students, and anyone interested in biology and medicine can utilize this plugin to access curated, lay-friendly information from a reliable knowledge graph. It facilitates exploration, learning, and understanding of the interconnected world of genes, diseases, and phenotypes. The plugin's ability to provide comprehensive information, associations, and related entities makes it a valuable resource for users looking to delve into biomedical data without relying on clinical decision-making or medical advice.
Example Prompt 1:
"What is the ontology identifier for the gene BRCA1?"
This prompt will use the Monarch Initiative Explorer to search for the ontology identifier of the gene BRCA1 and retrieve the relevant information.
Example Prompt 2:
"Find information about the disease cystic fibrosis."
This prompt will utilize the Monarch Initiative Explorer to search for detailed information about the disease cystic fibrosis, including ontology identifiers, associations, and related entities.
Example Prompt 3:
"Search for phenotypes related to Down syndrome."
This prompt will leverage the Monarch Initiative Explorer to search for phenotypes associated with Down syndrome, providing detailed information about the phenotypic profiles and related entities.
Example Prompt 4:
"Perform a semantic similarity search for the gene TP53."
This prompt will demonstrate how the Monarch Initiative Explorer can conduct a semantic similarity search for the gene TP53, allowing users to find similar genes or entities even if they are uncertain about the exact name or identifier.
Example Prompt 5:
"Tell me about the general information about the set of genes related to breast cancer."
This prompt will utilize the Monarch Initiative Explorer to retrieve general information about the set of genes associated with breast cancer, providing users with an overview of the gene-disease associations in the context of breast cancer.
